This is what we know so far. The "year 0" isnt a relevant event, just a random starting point. The events regarding MC are a guess of mine because we dont know MC age, but he said Isabel wasnt much older than him, so if she has 29 in the present, this timeline is based in MC having 25.
So, with this in mind, lets talk about facts first:
- When Luna was with his father (the day that M6 took her) the DeLuca were already an important family (there are a lot of references to this point).
- We know that the original Serpents founded the DeLuca family. So they did it, probably, after the war (or in that time).
At this point we can say (if you are with me and my numbers) that the war happened AT LEAST 19 years before the present time.
My guess is that taking the comments that Giacobbe said when talking with Cordia, refering to her as a young woman. I would guess that the war happened before Antonio birth. That means a minimum of 30 years in the past, when Cordia has between 15 to 19 years. This is my theory, the war wasnt long, the Serpents made that possible and the comments of Giacobbe of how impressive they were made me believe this. So the war was between 30-35 years in the past, and that means it was quick, then the treason of the Serpents, and the grils growing when the new Serpents were in the family.