For anyone getting an AV-/Malware detection. It's due to renpy making an (additional?) 32-bit .exe file. That file seems to ask for some system permissions when launched, hence the detection. That one is not needed to launch any VN compiled by the newer renpy version that makes it.
Unless you are running a 32bit OS, safely ignore it. You can also just delete it... not like it's going to matter for you. Otherwise, if you do run a 32bit OS, than you need to exclude it as a false positive in your exclusion list to be able to run that one executable...