It's from your home in the evening. You will have a few ways you can spend your evening time. One is to go to the lab and work in it. Need to go to lab, set up lab, collect materials, then make serums. Each step takes evening time and has to be done in that order. There's no use for serums until you've corrupted a girl enough, which also takes evening time. Once you have enough money and serums you can focus all your efforts on corrupting and transforming the girls and the more advanced plot and collecting new girls. You don't really have a choice as to which serum you use first on which girl, since it will prompt you "use blue serum?" etc. But I think that in general the idea is that you'll be able to use multiple serums on all of them as you progress, based on their current personality and state. I have all of them 2 or 3 steps along except for the tatoo parlor girl and the goth, the former of which you can't inject yet, and the latter of which you can only do the early stages with (but it's worth it ... she's my favorite).
In general my routine is like this: get up, check girl progress, go to school, train Frank (name?), train him more (you can max him out pretty soon but keep training him anyway for money ... there are a few other ways to make money too but this is the best), go home, either work in the lab or tutor whichever of the various girls I'm working on at the time. in addition to this there are a few other things you can do such as go to the sex shop, make phone calls or check messages, go to the deans' office, go to the dean's home, go to tattoo parlor, etc. some of these other things will be plot critical and others will just be nice bonuses. if you ever feel stuck check out the phone or dean's office or talk again to the girls after class, or just keep corrupting the girls in every way until you open up new convo options. don't worry if you get prompts that sometimes make no sense (like at the gym), because they will make sense later.