I don't normally do multiple play throughs. I usually pick a path, stick with it, and when I'm done, I'm done.
This game offers enough paths with enough variety that, not only do I want to play the other paths, but less stuff overlaps allowing for each path to be fulfilling, while also incentivizing playing each path to try to learn more.
It's a brilliant game structure.
The girls are hot, and the plot has me intrigued. It's actually a fantastically well done sci-fi plot for this sort of game.
This is high on my watch list, now.
My one gripe is that it can be hard to follow multiple paths at once, while others seem mutually exclusive. It would be slightly more satisfying if, on each playthrough, I could pick 2 to 4 girls and have it be "these are my focus for this playthrough," instead of starting over just to follow one girl's path, because someone after a few plays you seem to have done all but hers.
Still, it's fun to speculate on how the story will turn out.