It doesn't crash for me.
No issues, but I wouldn't suggest it because the patch is usually a bit behind the repack. Saves will carry over, but any functionality that was in the repack and not in the HF, whether by mods or DLC, will not be available. For example, the pregnancy mod now allows control of a girl's cycle so that you can set when she will be risky. That just got added into the latest version of the mod, which only got put into the repack a few days ago. I doubt the HF is up to date and it does include the pregnancy mod. You WILL lose the ability to alter a girl's cycle if you apply the patch and it hasn't been updated to include version 1.2 of the pregnancy mod. Also, it could be missing clothing or hair mods that a character might be equipped with. Any missing part will result in the girl having an empty space where that part goes, missing hairs will result in a hole in her head for example.