As for Medb...hm, i take her attitude as more of a facade in her diplomatic duty, they are on really bad terms with the templars (and the MC is included in that), they want the templars to fear them, and yeah she got a bit pissed about the life debt
![ROFL :ROFLMAO: :ROFLMAO:](data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7)
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Add to that she's kinda a millenium old and one of their most powerful and influental people and not particular fond of humans in general.
I honestly can't really fault her for that, if you see their culture and how they life and compare that to the humans as a whole (worse the ones in neverwhere)....well yeah, understandable they have no good view on humanity... i mean, even i don't have a particular good opinion about humanity as a whole ¯\_(ツ)_/¯