Is it some new specific wench I've never seen before or just the regular old wench? Because that one requires cum-covered skin/clothing or whatever. No idea how different she is the Hotel one though.
Remember how seemingly "same" enemies have "different" descriptors in their name: Wenches, for example, can be "QoS", "Horny", "Workaholic" and so on? Those are all different units in the context of spawning conditions. That being said - unless something changed between 5.0 and 5.2, Wenches have no other requirement
to spawn other than the Ass-to-Mouth fetish. What they
do have, similar to pretty much every enemy in the game, is a plethora of conditions that affect...well - other conditions: take QoS wench - she does not spawn in the Dungeon area unless your BBC addiction is 8+. Another example: enabling Bukkake fetish changes part of description from "and from her voluptuous, jizz-coated figure" to "and from the way semen is leaking from her holes".
Summary: A2M is the only requirement to spawn Wenches, everything else enables them to spawn in specific areas and/or perform additional actions.
This is why lack of information on fetishes frustrated me to no end: this game is riddled with conditions you cannot possibly figure out until after you played it for a long time, and while "enemy description" is something I totally like, "enemy spawning" is not something I appreciate being affected by that in the slightest.
P.S. When I say "spawn" - I mean natural spawns, roaming enemies, those are different from spawning for special events like losing a game of poker.