Bahamut Fabulous Flying blind here since I have never
ever run into that particular error message with any software myself, game or not. Sounds like you have enough "to run the game": Win10 x64 (same as me, and the game runs fine here). Beyond that, I suspect it to be a system security/permissions issue, maybe someone else can be of more help. This is where I would start fiddling with system security settings...assuming "running this one game" is worth the risk AND effort involved, to begin with.
Summary: Confused. No ideas. Sorry.