Well, I gave this a try after hearing on another thread, about a Strip Rock Paper Scissors game... which, I uh, have now learned is not part of the main game exactly. So, a little bummed there, but that's what I probably get for expecting that.
That aside, I've only done a single playthrough thus far, but it didn't feel too bad, truth be told. The characters are fairly interesting, even if Daz is still a bit weird for me to get used to in terms of looks. The plot also is interesting, although it is kind of a shame that it seems you can't really get to see 'all' the content in a run. I get some are mutually exclusive, but a shame you can't try to actually do your job, and have time to actually get to know the crew and all that.
About the only issue I noticed was in Chapter 3, where Sarah talked about our last VR session - which didn't happen, because I didn't visit her to trigger it I suppose, as it seems to be a mutually exclusive thing, or I spent too much time doing something else, unsure. But its also possible the flags can't really be that exact between chapters.