You will be able to get every girl in one playthrough, though the intent has always been that it would be difficult (but not at all impossible) on your first playthrough. But since you mention paths, the answer is no. Each girl can have multiple paths, and you can only get one of them in one playthrough. For example, Primrose can either be your friend, girlfriend, or FWB, but not all of those.I will use this moment to ask: will we be able to finish every single path during that limited time, or will we need to dedicate our efforts to only some of them and get others on the next runs? Or maybe it was not decided yet?